River of Death (1989)

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In the nightmarish last days of the Third Reich, a psychotic Nazi scientist escapes to the impenetrable jungles of the Amazon. Years later, a mysterious incurable disease breaks out among the natives and adventurer John Hamilton is hired to lead investigators on a search for the cause. Braving bloodthirsty rives pirates, hostile native tribes and headhunting cannibals, Hamilton, guides a group of explorers up the deadly Rio del Morte to the fabulous lost Inca city